@article{86416, keywords = {Animals, Drosophila, Models, Biological, Cell Membrane, Cell Division, Mitosis, Epithelial Cells, Cell Adhesion}, author = {Thomas Lecuit and Eric Wieschaus}, title = {Junctions as organizing centers in epithelial cells? A fly perspective.}, abstract = { Junctions isolate the apical from the basal-lateral surfaces and are required for the polarization of epithelial cells. Genetics of junction formation in Drosophila has identified numerous transmembrane and scaffolding proteins that assemble in membrane-associated complexes. This review focuses on recent findings suggesting that junctions are autonomous organizing centers for the establishment and maintenance of apical-basal polarity in epithelial cells as well as other polarized processes such as the orientation of the division apparatus. }, year = {2002}, journal = {Traffic}, volume = {3}, pages = {92-7}, month = {02/2002}, issn = {1398-9219}, language = {eng}, }